The central region of the Udon Thani Province has a series of rivers that are not bridged, making easy access to many places a long and arduous journey. To that end, it is very hard to visit more than perhaps two or three places in a single day. You will need to have a car to call your own as this really is the only practical way to get around the countryside. There are no trains and very few buses available except those that travel between the few towns that are dotted about.
The Red Lotus Sea is best visited as early as possible in the morning in early and the middle of December.
For a healthy dose of local history and culture, then head over to the Ban Chiang Museum, one of the most visited places in the region.
If you have a Thai wife or girlfriend, you will do well to suggest visiting Kham Chanot where she can earn some serious merit with Buddha.